With what type of food should Contrave not be taken?

Contrave, which is a combination of bupropion and naltrexone, is designed to aid in weight management by suppressing appetite and reducing food cravings. The interaction between Contrave and high-fat foods is significant because high-fat meals can increase the absorption and systemic exposure to naltrexone, one of the components of Contrave. This can potentially lead to an increased risk of side effects related to the medication, as well as impacting its effectiveness.

When patients are instructed about their diet while taking Contrave, it's important that they understand which types of foods may alter the drug's pharmacokinetics. High-fat meals can cause fluctuations in how the medication is metabolized, making it less predictable. Therefore, it is generally advised to avoid combining Contrave with high-fat foods to minimize any adverse effects and ensure the medication operates as intended.

In contrast, high protein, high carbohydrate, and low-calorie foods do not have the same impact on the absorption and effectiveness of Contrave, making them more suitable options for patients on this medication.