Which of the following medications is considered positive for weight management in migraine patients?

Amitriptyline is a tricyclic antidepressant often used for the prophylactic treatment of migraines. One of the benefits of amitriptyline is its potential positive impact on weight management. In certain circumstances, it may lead to weight loss or stabilization in weight for some individuals, particularly in those who may otherwise be engaging in binge eating or experiencing significant weight fluctuations related to migraine episodes.

Additionally, amitriptyline can help alleviate migraine symptoms, allowing patients to engage more actively in lifestyle modifications, including those beneficial for weight management, such as increased physical activity. Maintaining a stable weight can be especially important for migraine patients, as weight fluctuations can potentially exacerbate their migraine conditions.

The other medications listed may not provide positive outcomes for weight management in migraine patients. Triptans, while effective for aborting migraine attacks, can sometimes lead to weight gain due to their effects on serotonin levels and appetite. CGRP antagonists are newer migraine treatments that do not have well-established effects on weight, and NSAIDs are generally used for their analgesic properties without specific implications for weight management.