Which lab tests are indicated for children with risk factors and a BMI in the 85th-95th percentile?

The selection of a fasting lipid panel, along with AST (aspartate aminotransferase), ALT (alanine aminotransferase), fasting glucose, and BUN (blood urea nitrogen) and creatinine (Cr), is appropriate for children who are classified as overweight, particularly those whose BMI falls between the 85th and 95th percentiles and exhibit additional risk factors for metabolic and cardiovascular conditions.

When assessing children at risk for obesity-related health issues, a comprehensive evaluation that includes liver function tests (AST and ALT) is important, as these can indicate non-alcoholic fatty liver disease, which is prevalent in this demographic. Additionally, measuring fasting glucose is essential for screening potential insulin resistance or prediabetes, conditions associated with obesity. BUN and creatinine levels are evaluated to assess kidney function, which can be affected in children with obesity, particularly those with metabolic syndrome.

Including a fasting lipid panel is critical in this context, as children at risk are prone to dyslipidemia, which can lead to cardiovascular disease later in life. The combination of these tests provides a thorough assessment of metabolic health and helps in the early identification of complications associated with being overweight or obese.

In contrast, a fasting lipid panel alone or the