Which genetic syndrome is characterized by short stature and bradydactyly?

Albright-Hereditary Osteodystrophy is characterized by a distinct combination of features, including short stature and bradydactyly, which refers to shortened fingers and toes. This genetic syndrome is a result of a mutation affecting the GNAS gene, which leads to the impairment of certain endocrine functions, affecting growth and development.

Individuals with this condition typically present with not only short stature but also a characteristic shape of the bones, leading to the abnormality in digit length. Bradydactyly is a notable feature often observed in patients with this syndrome, making it a key distinguishing characteristic. Other elements of Albright-Hereditary Osteodystrophy may include obesity and resistance to parathyroid hormone, but the defining features here are the short stature and specific digit morphology.

In contrast, the other genetic syndromes listed have different hallmark characteristics: Marfan syndrome primarily affects connective tissues and is not associated with bradydactyly; Turner syndrome is associated with short stature but differs in the absence of normal ovarian function and does not typically include bradydactyly; Crouzon syndrome is known for craniosynostosis and specific facial features and does not prominently feature short stature or bradydactyly. Thus, Al