Which gastrointestinal hormone is released from L-cells?

The correct answer is PYY, which stands for peptide YY. This hormone is released by L-cells found primarily in the intestinal lining, particularly in the ileum and colon. Its primary role is to help regulate appetite and food intake. PYY is secreted in response to feeding and acts to reduce hunger by inhibiting gastric motility and promoting satiety. It also plays a role in slowing down the gastrointestinal tract, allowing for more efficient digestion and absorption of nutrients.

Understanding the function of gastrointestinal hormones in appetite and energy homeostasis is crucial, especially in the context of obesity medicine, where these mechanisms can be targeted for interventions. This highlights the significance of PYY, as its levels can influence body weight regulation and metabolic processes.

In contrast, hormones like CCK, GIP, and gastrin originate from different cells within the gastrointestinal tract. CCK is produced by I-cells and is involved in digestion and satiety after meals, GIP is secreted from K-cells and stimulates insulin secretion in response to glucose, while gastrin is released by G-cells and is primarily responsible for stimulating gastric acid secretion. Thus, understanding the specific source and function of each hormone is vital for comprehending their roles in digestion and obesity