Which condition is characterized by an increased risk of tumors in children?

Beckwith-Wiedemann syndrome is characterized by an increased risk of tumors in children, particularly embryonal tumors such as Wilms tumor, hepatoblastoma, and neuroblastoma. This syndrome is a growth disorder that leads to an increased size of various organs and tissues, and one of the notable aspects of the condition is its association with an imbalance in genomic imprinting on chromosome 11, which plays a critical role in regulating growth.

Children with Beckwith-Wiedemann syndrome are monitored closely for the development of tumors, especially during the early years of life, as the risk is significantly higher than in the general population. Early diagnosis and regular surveillance for tumors can help in managing this risk effectively.

The other conditions listed do not carry the same level of tumor risk, making them less relevant in the context of this question. For instance, while Prader-Willi syndrome and Angelman syndrome are both genetic disorders that arise from abnormalities in chromosome 15, they are primarily associated with developmental and metabolic challenges rather than an increased cancer risk. Borgeson-Forssman-Lehmann syndrome is a rare genetic disorder with its own specific symptoms but lacks the tumor association found in Beckwith-Wiedemann syndrome, clearly distinguishing it as the correct answer to the