Which condition is associated with pseudohypoparathyroidism?

Pseudohypoparathyroidism is a genetic condition characterized by the body's resistance to parathyroid hormone (PTH), leading to low calcium levels and high phosphate levels due to the inability of the kidneys and bones to respond appropriately to this hormone. Albright-Hereditary Osteodystrophy is specifically associated with this condition and is characterized by features such as short stature, obesity, and skeletal abnormalities.

The condition is caused by a mutation that results in a deficiency in the action of PTH, although the levels of the hormone itself may be normal or elevated. Individuals with Albright-Hereditary Osteodystrophy typically show signs of end-organ resistance to PTH, which speaks directly to the definition of pseudohypoparathyroidism. Consequently, the association is well documented in medical literature, making this choice the most accurate answer regarding the condition linked to pseudohypoparathyroidism.

Other conditions listed, such as Marfan syndrome, Down syndrome, and Turner syndrome, have their own distinct genetic underpinnings and clinical manifestations, unrelated to the mechanisms of pseudohypoparathyroidism. Therefore, Albright-Hereditary Osteodystrophy is the only one among the choices that directly applies