What kind of syndrome makes orlistat contraindicated?

Orlistat is a weight loss medication that works by inhibiting the absorption of dietary fats in the intestines. In the case of chronic malabsorption syndrome, the use of orlistat can exacerbate the already compromised ability of the body to absorb nutrients effectively. This syndrome signifies an existing condition where the body does not absorb enough nutrients from the food consumed, leading to potential deficiencies and associated complications. The introduction of orlistat in these patients can aggravate nutrient malabsorption, worsening their health status and nutritional deficiencies. Therefore, it is contraindicated in individuals with this syndrome to prevent further complications and ensure patient safety.