What is the effect of oxyntomodulin on hormone secretion?

Oxyntomodulin is a peptide hormone that is produced in the gut and plays a significant role in appetite regulation and glucose metabolism. Its effects are similar to those of glucagon-like peptide-1 (GLP-1) and glucagon. By acting as an agonist on GLP-1 receptors, oxyntomodulin enhances insulin secretion in response to food intake, thereby playing a crucial role in the regulation of blood glucose levels.

Additionally, it has been observed that oxyntomodulin can modulate gastric emptying and reduce appetite, further contributing to its role in energy balance and weight management. Its action on the receptors positioned in the pancreas resembles that of GLP-1 and glucagon, helping to stimulate insulin secretion and prevent hyperglycemia.

The other options reflect incorrect physiological effects of oxyntomodulin, as it does not inhibit ghrelin secretion and does not enhance cortisol secretion. While it does influence insulin, it does so in a manner that helps reduce blood glucose, instead of outright inhibiting its secretion. Understanding these details highlights the importance of oxyntomodulin in metabolic processes, particularly in obesity management.