In which part of the gastrointestinal tract is CCK produced?

Cholecystokinin (CCK) is a hormone that plays a significant role in digestion and is primarily produced in the cells of the intestinal mucosa, specifically in the duodenum and jejunum, which are parts of the small intestine. When food enters the duodenum, particularly fatty acids and amino acids, it stimulates the release of CCK. This hormone then facilitates the digestion of fats and proteins by stimulating the gallbladder to release bile and the pancreas to secrete digestive enzymes, thus aiding in the digestion and absorption of nutrients.

The duodenum functions as the first section of the small intestine where the majority of enzymatic digestion occurs, making it a critical site for CCK production. The jejunum, following the duodenum, is also involved in further digestion and nutrient absorption, supporting the role of CCK in the digestive process.

Other regions mentioned, such as the stomach, colon, and pyloric region, do not produce CCK; instead, the stomach primarily secretes gastric juices, the colon focuses on the absorption of water and electrolytes, and the pyloric region pertains more to the passage of food from the stomach to the small intestine rather than hormone production. Therefore, recognizing the primary site of